Satiety Assessment

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Our satiety assessment protocol provides a behavioural measure is independent of food intake that is sensitive to the experience of satiety. The target measure is latency to make a response in learning task requiring mental effort. More specifically, the task requires the animals to hold information in memory for either 5, 55 or 105 seconds and then respond. Animals that are highly food motivated will respond more rapidly than animals experience satiety.

Data from an experiment in which animals are tested either before feeding or following a period of overfeeding, in which animals were given 1 hour to consume a quantity of food containing twice their daily energy requirements. In the overfeeding condition, the animals respond more slowly than in the prefeeding condition, and the differences when the delay is increased, requiring greater effort.