Brain Imaging

Brain imaging technologies can be routinely used in preclinical drug assessment and are no longer prohibitively expensive. CanCog has capabilities to advance your research program with the application of brain imaging technologies, such as MRI and PET.

CanCog has extensive experience with imaging of dogs and cats. We can image rodents and other species as well.

The following imaging technologies are currently available in dogs, cats and rodents.

Magnetic Resonance Imaging

T-1 Images

Used for obtaining brain maps for structural comparisons, developmental analyses and assessing macroscopic responses to interventions

T-2 and Proton Density

Used to distinguish gray and white matter

Diffusion Tensor Imaging

Used to quantify myelination and white matter tracts

Magnetic Resonance Spectroscopy

A tool for quantifying brain metabolites and therapeutic concentrations

SPECT and PET

Both of these technologies are used to obtain brain distribution of tracer compounds, and can be used for studies of blood flow, brain metabolism and brain distribution.

Functional Imaging

Provides measures of dynamic changes within the nervous system. Can be used to measure localized changes in blood flow and oxygen intake.

Assessment of compound distribution / receptor binding

Dynamic Contrast Enhancement

Uses brain imaging to resolve the brain distribution of a marker substance as a function of time. Used to assess blood flow, integrity of blood brain barrier, and regional cerebral blood volume

Image Analysis

Image analysis services are available on request.

Let us help you evaluate the utility of these various imaging technologies for your product development requirements.