Research

Assessment of Feline Cognitive Ability

In order to improve and extend our services, CanCog has instituted a program of research into feline cognition. In an initial study, CanCog developed two unique assessment tools, a specialized feline T-maze and a feline modification of the cognitive test apparatus developed for use with dogs - the feline general test apparatus.

Role of Cholinergic System in Canine Cognitive Aging

Human pathological aging is accompanied by a decline in cholinergic function, which provides a basis for treating Alzheimer's disease with compounds that enhance acetylcholine. CanCog is evaluating the effects of pharmacological manipulation of acetylcholine in young and aged beagle dogs, and at the more molecular level, changes in acetylcholine receptors associated with age and cognitive decline. This research may help develop new ways of treating cognitive dysfunction in companion animals.

Behavioral enrichment as an intervention in promoting successful aging

We have been exploring the importance of environment, social and experiential factors in the development of cognitive dysfunction in dogs. One study found that age-dependent cognitive dysfunction was maximally reduced by a combination of behavioral enrichment and maintenance on food enriched with a broad spectrum of antioxidants. Further analysis has suggested that behavioral enrichment is effective because it can promote cellular growth and possibly the development of new brain cells.